The New England journal of medicine, 2020-10, Vol.383 (15), p.1436-1446
2020
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Details
- Autor(en) / Beteiligte
- Titel
- Dapagliflozin in Patients with Chronic Kidney Disease
- Ist Teil von
- The New England journal of medicine, 2020-10, Vol.383 (15), p.1436-1446
- Ort / Verlag
- United States: Massachusetts Medical Society
- Erscheinungsjahr
- 2020
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- In this trial, patients with CKD (with or without type 2 diabetes) were randomly assigned to receive dapagliflozin or placebo. The primary composite outcome — a sustained decline in the estimated GFR of at least 50%, end-stage kidney disease, or death from renal or cardiovascular causes — was less frequent with dapagliflozin.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0028-4793eISSN: 1533-4406DOI: 10.1056/NEJMoa2024816Titel-ID: cdi_proquest_journals_2449268333
- Format
- –
- Schlagworte
- Aged, Albumin, Antidiabetics, Benzhydryl Compounds - adverse effects, Benzhydryl Compounds - pharmacology, Benzhydryl Compounds - therapeutic use, Cardiovascular Diseases - etiology, Cardiovascular Diseases - mortality, Cardiovascular Diseases - prevention & control, Clinical trials, Congestive heart failure, Creatinine, Death, Diabetes, Diabetes mellitus (non-insulin dependent), Diabetes Mellitus, Type 2 - complications, Diabetes Mellitus, Type 2 - drug therapy, Diabetic Nephropathies - drug therapy, End-stage renal disease, Female, Glomerular filtration rate, Glomerular Filtration Rate - drug effects, Glucose, Glucosides - adverse effects, Glucosides - pharmacology, Glucosides - therapeutic use, Humans, Kaplan-Meier Estimate, Kidney diseases, Kidney Failure, Chronic - mortality, Laboratories, Male, Middle Aged, Population, Regression Analysis, Renal Insufficiency, Chronic - complications, Renal Insufficiency, Chronic - drug therapy, Sodium-Glucose Transporter 2 Inhibitors - adverse effects, Sodium-Glucose Transporter 2 Inhibitors - pharmacology, Sodium-Glucose Transporter 2 Inhibitors - therapeutic use, Statistical analysis