The New England journal of medicine, 2020-07, Vol.383 (5), p.415-425
2020
Details
- Autor(en) / Beteiligte
- Titel
- Single-Dose Nirsevimab for Prevention of RSV in Preterm Infants
- Ist Teil von
- The New England journal of medicine, 2020-07, Vol.383 (5), p.415-425
- Ort / Verlag
- United States: Massachusetts Medical Society
- Erscheinungsjahr
- 2020
- Link zum Volltext
- Quelle
- Electronic Journals Library
- Beschreibungen/Notizen
- Nirsevimab, a monoclonal antibody with an extended half-life, is designed to protect infants from respiratory syncytial virus disease after a single intramuscular dose. This placebo-controlled trial involving 1447 preterm infants at 164 sites in 23 countries assessed the effectiveness of nirsevimab over 150 days after the dose was administered.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0028-4793eISSN: 1533-4406DOI: 10.1056/NEJMoa1913556Titel-ID: cdi_proquest_journals_2428565840
- Format
- –
- Schlagworte
- Antibodies, Antibodies, Monoclonal - administration & dosage, Antibodies, Monoclonal - adverse effects, Antibodies, Monoclonal, Humanized - administration & dosage, Antibodies, Monoclonal, Humanized - adverse effects, Antiviral Agents - administration & dosage, Antiviral Agents - adverse effects, FDA approval, Female, Gestation, Gestational age, Health aspects, Health care, Hospitalization, Hospitalization - statistics & numerical data, Humans, Hypersensitivity, Incidence, Infant, Infant, Newborn, Infant, Premature, Infants, Infants (Premature), Infections, Injection, Injections, Intramuscular, Kaplan-Meier Estimate, Laboratories, Male, Monoclonal antibodies, Newborn babies, Pediatric research, Pharmacokinetics, Poisson Distribution, Premature babies, Prevention, Prophylaxis, Respiratory diseases, Respiratory syncytial virus, Respiratory syncytial virus infection, Respiratory Syncytial Virus Infections - epidemiology, Respiratory Syncytial Virus Infections - prevention & control, Respiratory Syncytial Virus, Human, Respiratory tract diseases, Respiratory Tract Infections - epidemiology, Respiratory Tract Infections - prevention & control, Respiratory Tract Infections - virology, Vaccines, Viral Fusion Proteins - antagonists & inhibitors, Vitamin E, Writers