Advanced synthesis & catalysis, 2020-07, Vol.362 (14), p.3004-3010
2020
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Details
- Autor(en) / Beteiligte
- Titel
- Iron‐Mediated Cyanoalkylsulfonylation/Arylation of Active Alkenes with Cycloketone Oxime Derivatives via Sulfur Dioxide Insertion
- Ist Teil von
- Advanced synthesis & catalysis, 2020-07, Vol.362 (14), p.3004-3010
- Ort / Verlag
- Heidelberg: Wiley Subscription Services, Inc
- Erscheinungsjahr
- 2020
- Quelle
- Access via Wiley Online Library
- Beschreibungen/Notizen
- Iron‐mediated radical cyanoalkylsulfonylation/arylation of active olefins with cycloketone oxime derivatives via cleavage of C−C single bond and insertion of SO2 is developed for the preparation of cyanoalkylsulfonylated oxindoles. This difunctionalization of carbon−carbon double bond via a radical pathway involves cyclobutanone oxime ester fragmentation, sulfonyl radical generation and radical addition/5‐exo cyclization. The methodology displays good functional group tolerance and does not require any external bases or oxidants.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1615-4150eISSN: 1615-4169DOI: 10.1002/adsc.202000369Titel-ID: cdi_proquest_journals_2428031240
- Format
- –
- Schlagworte
- acrylamides, Alkenes, Carbon, cycloketone oxime esters, Derivatives, Functional groups, Insertion, insertion of sulfur dioxide, Iron, iron-mediated, Oxidizing agents, oxindoles, Sulfur dioxide