Details

Autor(en) / Beteiligte

• Yang, Ziwei
• Tang, Zijuan
• Cao, Xiuping
• Xie, Qi
• Hu, Chuan
• Zhong, Zhisheng
• Tan, Jun
• Zheng, Yuehui

Titel

Controlling chronic low‐grade inflammation to improve follicle development and survival

Ist Teil von

• American journal of reproductive immunology (1989), 2020-08, Vol.84 (2), p.e13265-n/a

Ort / Verlag

Denmark: Wiley Subscription Services, Inc

Erscheinungsjahr

2020

Quelle

Wiley Online Library

Beschreibungen/Notizen

• Chronic low‐grade inflammation is one cause of follicle development disturbance. Chronic inflammation exists in pathological conditions such as premature ovarian failure, physiological aging of the ovaries, and polycystic ovary syndrome. Inflammation of the whole body can affect oocytes via the follicle microenvironment, oxidative stress, and GM‐CSF. Many substances without toxic side‐effects extracted from natural organisms have gradually gained researchers’ attention. Recently, chitosan oligosaccharide, resveratrol, anthocyanin, and melatonin have been found to contribute to an improvement in inflammation. This review discusses the interrelationships between chronic low‐grade inflammation and follicle development, the underlying mechanisms, and methods that may improve follicle development by controlling the level of chronic low‐grade inflammation.