The New England journal of medicine, 2020-06, Vol.382 (26), p.2504-2513
- Badve, Sunil V
- Pascoe, Elaine M
- Tiku, Anushree
- Boudville, Neil
- Brown, Fiona G
- Cass, Alan
- Clarke, Philip
- Dalbeth, Nicola
- Day, Richard O
- de Zoysa, Janak R
- Douglas, Bettina
- Faull, Randall
- Harris, David C
- Hawley, Carmel M
- Jones, Graham R.D
- Kanellis, John
- Palmer, Suetonia C
- Perkovic, Vlado
- Rangan, Gopala K
- Reidlinger, Donna
- Robison, Laura
- Walker, Robert J
- Walters, Giles
- Johnson, David W
2020
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- Autor(en) / Beteiligte
- Badve, Sunil V
- Pascoe, Elaine M
- Tiku, Anushree
- Boudville, Neil
- Brown, Fiona G
- Cass, Alan
- Clarke, Philip
- Dalbeth, Nicola
- Day, Richard O
- de Zoysa, Janak R
- Douglas, Bettina
- Faull, Randall
- Harris, David C
- Hawley, Carmel M
- Jones, Graham R.D
- Kanellis, John
- Palmer, Suetonia C
- Perkovic, Vlado
- Rangan, Gopala K
- Reidlinger, Donna
- Robison, Laura
- Walker, Robert J
- Walters, Giles
- Johnson, David W
- Titel
- Effects of Allopurinol on the Progression of Chronic Kidney Disease
- Ist Teil von
- The New England journal of medicine, 2020-06, Vol.382 (26), p.2504-2513
- Ort / Verlag
- United States: Massachusetts Medical Society
- Erscheinungsjahr
- 2020
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- This randomized trial assessed whether urate-lowering treatment with allopurinol could attenuate eGFR decline in at-risk patients with stage 3 or 4 chronic kidney disease. Allopurinol did not slow the decline in eGFR as compared with placebo.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0028-4793eISSN: 1533-4406DOI: 10.1056/NEJMoa1915833Titel-ID: cdi_proquest_journals_2417025446
- Format
- –
- Schlagworte
- Aged, Albumin, Allopurinol, Allopurinol - adverse effects, Allopurinol - therapeutic use, Clinical trials, Confidence intervals, Creatinine, Design, Diabetes Mellitus, Type 1 - blood, Diabetes Mellitus, Type 1 - drug therapy, Diabetes Mellitus, Type 1 - physiopathology, Diabetic Nephropathies - drug therapy, Diabetic Nephropathies - physiopathology, Disease Progression, Double-Blind Method, Drug dosages, Enzyme Inhibitors - adverse effects, Enzyme Inhibitors - therapeutic use, Epidemiology, Epidermal growth factor receptors, Female, Glomerular filtration rate, Glomerular Filtration Rate - drug effects, Gout, Gout Suppressants - adverse effects, Gout Suppressants - therapeutic use, Humans, Kidney diseases, Male, Medical research, Middle Aged, Patients, Renal Insufficiency, Chronic - drug therapy, Renal Insufficiency, Chronic - physiopathology, Renin-Angiotensin System, Treatment Failure, Uric acid, Uric Acid - blood, Xanthine Oxidase - antagonists & inhibitors