Details

Autor(en) / Beteiligte

• Palamarchuk, I. V.
• Ogurtsova, D. N.
• Seilkhanov, T. M.
• Kulakov, I. V.

Titel

Synthesis of N-Derivatives of Cytisine, Anabasine, and Salsoline Alkaloids with Pharmacophore 3-Aminopyridine-2(1H)-one and 5-Methyl-7-phenyloxazole[5,4-b]pyridine Cycles

Ist Teil von

• Russian journal of general chemistry, 2019-12, Vol.89 (12), p.2487-2491

Ort / Verlag

Moscow: Pleiades Publishing

Erscheinungsjahr

2019

Quelle

SpringerNature Journals

Beschreibungen/Notizen

• The reaction of nucleophilic substitution of 2-chloro- N -(6-methyl-2-oxo-4-phenyl-1,2-dihydropyridin-3-yl)acetamide and 2-(chloromethyl)-5-methyl-7-phenyloxazolo[5,4- b ]pyridine with cytisine, anabasine, and salsoline alkaloids has afforded the corresponding derivatives. Structure of the obtained compounds has been confirmed by means of 1 H and 13 C NMR spectroscopy.