Details

Autor(en) / Beteiligte

• Zhu, You‐Quan
• Hui, Li‐Wen
• Niu, Yun‐Xia
• Lv, Lin‐Ge
• Zhu, Kun

Titel

Reaction of Cycloalkene‐1‐carboxamides with Aryl Boronates via Rhodium(III)‐Catalyzed C−H Activation: A Versatile Route to 3,4‐Cycloalkaquinolin‐2(1H)‐ones

Ist Teil von

• Advanced synthesis & catalysis, 2019-12, Vol.361 (23), p.5400-5405

Ort / Verlag

Heidelberg: Wiley Subscription Services, Inc

Erscheinungsjahr

2019

Link zum Volltext

Quelle

Wiley Online Library - AutoHoldings Journals

Beschreibungen/Notizen

• Under rhodium(III) catalysis, substituted N‐methoxycycloalkene‐1‐carboxamides successfully reacted with aryl boronic acid pinacol esters to provide 3,4‐cycloalkaquinolin‐2(1H)‐ones via direct functionalization of the β‐alkenyl C−H bond and form C−C/C−N bond in one pot. The gram‐scale synthesis of the title compound demonstrated the great synthetic utility of this methodology.