Details

Autor(en) / Beteiligte

• PEREZ, J. Xavier
• ROIG, Teresa
• MANZANO, Anna
• DALMAU, Mireia
• BOADA, Jordi
• VENTURA, Francesc
• ROSA, Jose L
• BERMUDEZ, Jordi
• BARTRONS, Ramon

Titel

Overexpression of fructose 2,6-bisphosphatase decreases glycolysis and delays cell cycle progression

Ist Teil von

• American Journal of Physiology: Cell Physiology, 2000-11, Vol.48 (5), p.C1359-C1365

Ort / Verlag

Bethesda, MD: American Physiological Society

Erscheinungsjahr

2000

Quelle

Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals

Beschreibungen/Notizen

• The ability to overexpress 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase (PFK-2)(FB-Pase-2) or a truncated form of the enzyme with only the bisphosphatase domain allowed us to analyze the relative role of the kinase and the bisphosphatase activities in regulating fructose 2,6-bisphosphate (Fru-2,6-P2) concentration and to elucidate their differential metabolic impact in epithelial Mv1Lu cells.