Details

Autor(en) / Beteiligte

• Colakoglu, O.
• Tankurt, E.
• Unsal, B.
• Ugur, F.
• Kupelioglu, A.
• Buyrac, Z.
• Akpinar, Z.

Titel

Toxic hepatitis associated with paroxetine

Ist Teil von

• International journal of clinical practice (Esher), 2005-07, Vol.59 (7), p.861-862

Ort / Verlag

Oxford, UK, Malden, USA: Blackwell Science Ltd

Erscheinungsjahr

2005

Quelle

Wiley HSS Collection

Beschreibungen/Notizen

• Summary Hepatotoxicity is a rare complication of paroxetine, a selective serotonin reuptake inhibitor. Regarded as safe in therapeutic use, there have been reports of cases of severe hepatic dysfunction with gross elevations of transaminase levels that may be related to this drug. We report here severe adverse cholestatic and hepatocellular injury in a patient taking paroxetine probably due to an immune‐mediated hypersensitivity reaction.