Details

Autor(en) / Beteiligte

• Andersen, Christina
• Søndergaard, Helle Bach
• Bang Oturai, Ditte
• Laursen, Julie Hejgaard
• Gustavsen, Stefan
• Larsen, Nanna Katrine
• Magyari, Melinda
• Just-Østergaard, Emilie
• Thørner, Lise Wegner
• Sellebjerg, Finn
• Ullum, Henrik
• Oturai, Annette Bang

Titel

Alcohol consumption in adolescence is associated with a lower risk of multiple sclerosis in a Danish cohort

Ist Teil von

• Multiple sclerosis, 2019-10, Vol.25 (12), p.1572-1579

Ort / Verlag

London, England: SAGE Publications

Erscheinungsjahr

2019

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Background and objective: Due to the possible existence of a vulnerable period of multiple sclerosis (MS) susceptibility in adolescence and because Danish teenagers have a high alcohol consumption, we investigated the association between alcohol consumption at ages 15–19 and the risk of developing MS. Methods: A total of 1717 patients with MS and 4685 healthy blood donors filled in a comprehensive environmental and lifestyle questionnaire. Data were analysed by logistic regression models and adjusted for selected confounders. Results: We found an inverse association between alcohol consumption in adolescence and risk of developing MS in both women (p < 0.001) and men (p = 0.012). Women with low alcohol consumption had an odds ratio (OR) of 0.56 (95% confidence interval (CI): 0.47–0.66) compared with non-drinking women. The ORs were similar for women with moderate (OR = 0.49, 95% CI: 0.38–0.62) and high consumption (OR = 0.57, 95% CI: 0.38–0.84). Men with low alcohol consumption had an OR of 0.69 (95% CI: 0.53–0.89) compared with non-drinking men but no decreased risk was found for men with moderate and high consumption. Conclusion: Alcohol consumption in adolescence was associated with lower risk of developing MS among both sexes.