Details

Autor(en) / Beteiligte

• Zhu, Tong‐Hao
• Zhang, Xiao‐Chen
• Cui, Xian‐Lu
• Zhang, Ze‐Yu
• Jiang, Hui
• Sun, Shan‐Shan
• Zhao, Li‐Li
• Zhao, Kai
• Loh, Teck‐Peng

Titel

Direct C(sp2)‐H Arylsulfonylation of Enamides via Iridium(III)‐Catalyzed Insertion of Sulfur Dioxide with Aryldiazonium Tetrafluoroborates

Ist Teil von

• Advanced synthesis & catalysis, 2019-08, Vol.361 (15), p.3593-3598

Ort / Verlag

Heidelberg: Wiley Subscription Services, Inc

Erscheinungsjahr

2019

Quelle

Wiley Online Library

Beschreibungen/Notizen

• An iridium(III)‐catalyzed three‐component reaction of enamides, aryldiazonium tetrafluoroborates, and 1,4‐diazabicyclo[2.2.2]octane bis(sulfur dioxide) (DABSO) for the direct C(sp2)−H arylsulfonylation of enamides is developed. This transformation provides a robust and straightforward approach for preparing a diverse array of β‐amidovinyl sulfones in moderate to excellent yields and high stereoselectivities without Light‐emitting diode (LED) radiation. This transformation also features mild conditions, broad substrate scopes, and excellent functional group tolerance.