The New England journal of medicine, 2019-06, Vol.380 (26), p.2506-2517
2019
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Details
- Autor(en) / Beteiligte
- Titel
- Early Sedation with Dexmedetomidine in Critically Ill Patients
- Ist Teil von
- The New England journal of medicine, 2019-06, Vol.380 (26), p.2506-2517
- Ort / Verlag
- United States: Massachusetts Medical Society
- Erscheinungsjahr
- 2019
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- In a randomized trial involving 4000 patients in the ICU who required sedation for mechanical ventilation, dexmedetomidine had no benefit on 90-day mortality as compared with usual care and was associated with more adverse events. Additional drugs were required for prescribed sedation levels in the two groups.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0028-4793eISSN: 1533-4406DOI: 10.1056/NEJMoa1904710Titel-ID: cdi_proquest_journals_2247764422
- Format
- –
- Schlagworte
- Adult, Aged, Anesthesia, Bradycardia, Bradycardia - chemically induced, Conscious Sedation, Councils, Critical Illness - mortality, Critical Illness - therapy, Delirium, Dexmedetomidine - adverse effects, Drug dosages, Drug Therapy, Combination, Female, Humans, Hypnotics and Sedatives - adverse effects, Hypotension, Hypotension - chemically induced, Intensive care, Intensive Care Units, Intention to Treat Analysis, Male, Mechanical ventilation, Medical research, Midazolam, Middle Aged, Mortality, Propofol, Respiration, Artificial, Sedatives, Time Factors, Treatment Outcome, Ventilators