Details

Autor(en) / Beteiligte

• Cook, Deborah J
• Fuller, Hugh D
• Guyatt, Gordon H
• Marshall, John C
• Leasa, David
• Hall, Richard
• Winton, Timothy L
• Rutledge, Frank
• Todd, Thomas
• Roy, Peter
• Lacroix, Jacques
• Griffith, Lauren
• Willan, Andrew

Titel

Risk Factors for Gastrointestinal Bleeding in Critically Ill Patients

Ist Teil von

• The New England journal of medicine, 1994-02, Vol.330 (6), p.377-381

Ort / Verlag

Boston, MA: Massachusetts Medical Society

Erscheinungsjahr

1994

Quelle

Free E-Journal (出版社公開部分のみ）

Beschreibungen/Notizen

• Gastrointestinal bleeding due to stress ulceration is an important complication in critically ill patients 1 , 2 . Prophylactic measures such as neutralization of gastric acid, reduction of gastric acid secretion, or cytoprotection are commonly recommended, on the basis of the positive results of randomized trials 3 – 15 . A recent meta-analysis reported a 50 percent reduction in the relative risk of clinically important bleeding among patients receiving prophylaxis 16 . Prophylaxis against stress ulcers, however, is expensive 17 and may have adverse effects, 18 and the risk of clinically important bleeding has decreased during the past decade independently of the use of prophylaxis 1 , 19 – . . .