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Three Months versus One Year of Oral Anticoagulant Therapy for Idiopathic Deep Venous Thrombosis
Ist Teil von
The New England journal of medicine, 2001-07, Vol.345 (3), p.165-169
Ort / Verlag
Boston, MA: Massachusetts Medical Society
Erscheinungsjahr
2001
Quelle
EZB Free E-Journals
Beschreibungen/Notizen
Extending oral anticoagulant therapy to 12 months is beneficial.
The optimal duration of treatment with oral anticoagulant agents after deep venous thrombosis reflects a balance between the risk of recurrence when treatment is discontinued and the risk of bleeding resulting from continued anticoagulant therapy.
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The risk of recurrent thromboembolism after the discontinuation of anticoagulant therapy is highly dependent on patient-specific risk factors.
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Patients who have thrombosis in the absence of known risk factors (i.e., who have idiopathic venous thrombosis) or in association with persistent risk factors (such as cancer and thrombophilia) are at higher risk of recurrence than patients with thrombosis associated with time-limited, reversible risk factors. . . .