Details

Autor(en) / Beteiligte

• Stevens, David A
• Schwartz, Howard J
• Lee, Jeannette Y
• Moskovitz, Bruce L
• Jerome, Dennis C
• Catanzaro, Antonino
• Bamberger, David M
• Weinmann, Allison J
• Tuazon, Carmelita U
• Judson, Marc A
• Platts-Mills, Thomas A.E
• Grossman, Jay
• Slavin, Raymond G
• Reuman, Peter
• DeGraff, Arthur C

Titel

A Randomized Trial of Itraconazole in Allergic Bronchopulmonary Aspergillosis

Ist Teil von

• The New England journal of medicine, 2000-03, Vol.342 (11), p.756-762

Ort / Verlag

Boston, MA: Massachusetts Medical Society

Erscheinungsjahr

2000

Quelle

MEDLINE

Beschreibungen/Notizen

• Allergic bronchopulmonary aspergillosis is a hypersensitivity disease of the lungs that is almost always caused by Aspergillus fumigatus (Table 1). Several sets of diagnostic criteria have been proposed, 2 – 4 incorporating the clinical, immunologic, and radiographic features of the disease, since no single test is sufficiently discriminating. Allergic bronchopulmonary aspergillosis is underdiagnosed; prospective studies indicate that 7 to 14 percent 5 of patients (or more 6 ) with corticosteroid-dependent asthma meet the generally accepted definitions, as do 6 percent of patients with cystic fibrosis. 7 The disease can progress from the acute phase to stages characterized by exacerbations and corticosteroid dependency and finally to . . .