Details

Autor(en) / Beteiligte

• Ranta, Dana
• Bonmati, Caroline

Titel

Acquired Melanonychia

Ist Teil von

• The New England journal of medicine, 2009-09, Vol.361 (12), p.1188-1188

Ort / Verlag

Waltham, MA: Massachusetts Medical Society

Erscheinungsjahr

2009

Quelle

EZB Electronic Journals Library

Beschreibungen/Notizen

• An 80-year-old woman presented with longitudinal melanonychia, or longitudinal dark pigmentation of the nails (arrows). She first noticed it more than a year after the start of hydroxyurea treatment for essential thrombocythemia. Although all nails can be affected, in this patient only the two thumbnails were involved. She had no other side effects of therapy, and no other mucocutaneous hyperpigmentation was observed. At the time of presentation, she was not taking other drugs implicated in nail discoloration and had no symptoms attributable to essential thrombocythemia. The platelet count was 420×10 9 per liter. Melanonychia is a rare side effect of hydroxyurea . . .