The New England journal of medicine, 2019-05, Vol.380 (19), p.1795-1803
- Ma, Henry
- Campbell, Bruce C.V
- Parsons, Mark W
- Churilov, Leonid
- Levi, Christopher R
- Hsu, Chung
- Kleinig, Timothy J
- Wijeratne, Tissa
- Curtze, Sami
- Dewey, Helen M
- Miteff, Ferdinand
- Tsai, Chon-Haw
- Lee, Jiunn-Tay
- Phan, Thanh G
- Mahant, Neil
- Sun, Mu-Chien
- Krause, Martin
- Sturm, Jonathan
- Grimley, Rohan
- Chen, Chih-Hung
- Hu, Chaur-Jong
- Wong, Andrew A
- Field, Deborah
- Sun, Yu
- Barber, P. Alan
- Sabet, Arman
- Jannes, Jim
- Jeng, Jiann-Shing
- Clissold, Benjamin
- Markus, Romesh
- Lin, Ching-Huang
- Lien, Li-Ming
- Bladin, Christopher F
- Christensen, Søren
- Yassi, Nawaf
- Sharma, Gagan
- Bivard, Andrew
- Desmond, Patricia M
- Yan, Bernard
- Mitchell, Peter J
- Thijs, Vincent
- Carey, Leeanne
- Meretoja, Atte
- Davis, Stephen M
- Donnan, Geoffrey A
2019
Details
- Autor(en) / Beteiligte
- Ma, Henry
- Campbell, Bruce C.V
- Parsons, Mark W
- Churilov, Leonid
- Levi, Christopher R
- Hsu, Chung
- Kleinig, Timothy J
- Wijeratne, Tissa
- Curtze, Sami
- Dewey, Helen M
- Miteff, Ferdinand
- Tsai, Chon-Haw
- Lee, Jiunn-Tay
- Phan, Thanh G
- Mahant, Neil
- Sun, Mu-Chien
- Krause, Martin
- Sturm, Jonathan
- Grimley, Rohan
- Chen, Chih-Hung
- Hu, Chaur-Jong
- Wong, Andrew A
- Field, Deborah
- Sun, Yu
- Barber, P. Alan
- Sabet, Arman
- Jannes, Jim
- Jeng, Jiann-Shing
- Clissold, Benjamin
- Markus, Romesh
- Lin, Ching-Huang
- Lien, Li-Ming
- Bladin, Christopher F
- Christensen, Søren
- Yassi, Nawaf
- Sharma, Gagan
- Bivard, Andrew
- Desmond, Patricia M
- Yan, Bernard
- Mitchell, Peter J
- Thijs, Vincent
- Carey, Leeanne
- Meretoja, Atte
- Davis, Stephen M
- Donnan, Geoffrey A
- Titel
- Thrombolysis Guided by Perfusion Imaging up to 9 Hours after Onset of Stroke
- Ist Teil von
- The New England journal of medicine, 2019-05, Vol.380 (19), p.1795-1803
- Ort / Verlag
- United States: Massachusetts Medical Society
- Erscheinungsjahr
- 2019
- Link zum Volltext
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- In a randomized trial involving patients with stroke and salvageable regions of brain detected on imaging, 39.4% of those who received alteplase had no or minor neurologic deficits at 90 days, as compared with 29.5% of those who received placebo. The trial was stopped at 73% of its intended recruitment target.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0028-4793eISSN: 1533-4406DOI: 10.1056/NEJMoa1813046Titel-ID: cdi_proquest_journals_2221965769
- Format
- –
- Schlagworte
- Aged, Aged, 80 and over, Automation, Brain - diagnostic imaging, Brain Ischemia - diagnostic imaging, Brain Ischemia - drug therapy, Brain research, Cerebral Hemorrhage - chemically induced, Clinical trials, Computed Tomography Angiography, Evidence-based medicine, Female, Fibrinolytic Agents - adverse effects, Fibrinolytic Agents - therapeutic use, Hemorrhage, Humans, Infusions, Intravenous, Intervention, Intravenous administration, Intravenous therapy, Ischemia, Magnetic Resonance Angiography, Male, Medical imaging, Medical research, Middle Aged, Nervous System Diseases - epidemiology, Nervous System Diseases - prevention & control, Neuroimaging, Neurosciences, NMR, Nuclear magnetic resonance, Patients, Perfusion, Perfusion Imaging, Sleep, Stroke, Stroke - diagnostic imaging, Stroke - drug therapy, Stroke - mortality, Therapeutic Equipoise, Thrombolysis, Thrombolytic drugs, Time-to-Treatment, Tissue Plasminogen Activator - adverse effects, Tissue Plasminogen Activator - therapeutic use