Future virology, 2018-04, Vol.13 (4), p.275-285
2018
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- Autor(en) / Beteiligte
- Titel
- Oral status and periodontal microbiota of HIV-infected youth infected by vertical transmission
- Ist Teil von
- Future virology, 2018-04, Vol.13 (4), p.275-285
- Ort / Verlag
- London: Future Medicine Ltd
- Erscheinungsjahr
- 2018
- Beschreibungen/Notizen
- This study evaluated the oral status and microbiota of HIV+ youth infected by vertical transmission. 34 HIV+ and 36 HIV- individuals (14-24 years of age) were examined for oral infections/lesions. Subgingival biofilm was collected and the microbiota determined by checkerboard DNA-DNA hybridization. Over 90% of the HIV+ youth were under highly active antiretroviral therapy, but 64.6% had AIDS and 47% presented oral manifestations. HIV+ youth showed more periodontal attachment loss and inflammation than HIV- (p < 0.05), and also high prevalence of caries. Most species were detected in higher prevalence in the microbiota of HIV+ than controls. HIV+ youth infected by vertical transmission presented more periodontal destruction and inflammation, and greater prevalence of microbial pathogens compared with HIV- individuals.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1746-0794eISSN: 1746-0808DOI: 10.2217/fvl-2018-0025Titel-ID: cdi_proquest_journals_2216540438
- Format
- –
- Schlagworte
- Acquired immune deficiency syndrome, Age, AIDS, Antibiotics, Antiretroviral agents, Antiretroviral drugs, Biofilms, Children & youth, Chronic illnesses, Dental caries, Deoxyribonucleic acid, Disease, Disease transmission, DNA, Drug therapy, Highly active antiretroviral therapy, HIV, HIV infection, Human immunodeficiency virus, Human subjects, Hybridization, Infections, Lesions, Microbiota, Microorganisms, oral health, Oral hygiene, oral microbiota, Periodontics, Quality of life, Studies, Teenagers, Young adults