Details

Autor(en) / Beteiligte

• Sharma, Rashmi P.
• Raut, Siddheshwar D.
• Mulani, Ramjan M.
• Kadam, Ambadas S.
• Mane, Rajaram S.

Titel

Sol–gel auto-combustion mediated cobalt ferrite nanoparticles: a potential material for antimicrobial applications

Ist Teil von

• International nano letters, 2019-06, Vol.9 (2), p.141-147

Ort / Verlag

Berlin/Heidelberg: Springer Berlin Heidelberg

Erscheinungsjahr

2019

Quelle

EZB Free E-Journals

Beschreibungen/Notizen

• In the era of nanotechnology, nanoparticles (NPs) of metals and metal oxides/chalcogenides are widely been used in medical applications where antibiotic-resistant microorganisms become a serious threat to the human health. Cobalt ferrite (CoFe 2 O 4 ) NPs, synthesized by a simple and cost-effective sol–gel auto-combustion method are envisaged for in vitro antimicrobial activities against Gram-positive bacteria ( Bacillus subtilis; Staphylococcus aureus ) and Gram-negative bacteria ( Escherichia coli; Pseudomonas aeruginosa ). The structure, morphology, elemental analyses and surface area of CoFe 2 O 4 NPs are initially screened. The antimicrobial efficiency of CoFe 2 O 4 NPs is found to be optimum against the Gram-negative bacteria Escherichia coli (15 mm). In addition, membrane leakage assays performed to evaluate the intracellular cytoplasmic leakage with CoFe 2 O 4 NPs demonstrate the ability to destroy the bacterial membrane integrity, confirming their antimicrobial potential.