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Alterations of immunoglobulin G and immunoglobulin M levels in the breast milk of mothers with exclusive breastfeeding compared to mothers with non‐exclusive breastfeeding during 6months postpartum: The Jordanian cohort study
Ist Teil von
American journal of human biology, 2019-01, Vol.31 (1)
Ort / Verlag
Hoboken: Wiley Subscription Services, Inc
Erscheinungsjahr
2019
Quelle
Wiley-Blackwell Journals
Beschreibungen/Notizen
ObjectivesThe purpose of this study was to measure changes in the concentration of immunoglobulin G (IgG) and immunoglobulin M (IgM) in the mature breast milk of Jordanian mothers during the first 6 months after giving birth between exclusively breastfeeding (EBF) mothers and non‐exclusively breastfeeding (non‐EBF) mothers.MethodsA longitudinal follow‐up design was used to measure changes in the concentration of IgG and IgM in the mothers' mature milk during the first 6 months after giving birth. Sixty‐nine lactating mothers were recruited in this study. Breast milk samples were collected by mothers themselves in the first, fourth, and sixth months of lactation to measure IgG and IgM concentrations using the enzyme‐linked immunosorbent assay (ELISA) technique.ResultsThere was a significant difference in IgG and IgM concentrations between EBF and non‐EBF mothers. IgG was higher in the EBF mothers' milk than in the milk of non‐EBF mothers, whereas IgM was not affected by the type of baby feeding.ConclusionThe concentration of immunoglobulins changes in human breast milk along with breastfeeding intervals. EBF enhances the concentration of IgG in breast milk compared to non‐EBF.