Details

Autor(en) / Beteiligte

• Rivers, Jason K
• Mistry, Bhavik D
• Hung Tawny
• Vostretsova Kateryna
• Mistry Nisha

Titel

A 13-Year Retrospective Study of Basal Cell Carcinoma in a Canadian Dermatology Practice

Ist Teil von

• Journal of cutaneous medicine and surgery, 2016-05, Vol.20 (3), p.233-240

Ort / Verlag

Thousand Oaks: SAGE PUBLICATIONS, INC

Erscheinungsjahr

2016

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Background:It is unknown whether the histologic subtypes of basal cell carcinoma (BCC) arise from a common progenitor cell or whether other factors play a role in their development.Objective:To investigate the relationship between the different BCC histopathologic subtypes and anatomical distribution of BCCs in a Canadian dermatology practice.Methods:The charts of all patients diagnosed with BCC between 1993 and 2005 from a single private dermatology practice in Vancouver, Canada, were reviewed. Descriptive data analysis was undertaken to look at the distribution of histologic subtypes based on age, gender, and anatomical location.Results:Nodular BCCs accounted for 58% of all tumors. Sixty-six percent of these were situated on the head/neck (odds ratio [OR] = 3.0, 95% confidence interval [CI] = 2.1-4.3, P < .0001). Infiltrative (OR = 2.4, 95% CI = 1.5-4.1, P = .0003) and superficial BCCs were more common in women (OR = 3.7, 95% CI = 2.5-5.7, P < .0001), affected the trunk (OR = 3.2, 95% CI = 2.1-4.9, P < .0001), and appeared in younger individuals (OR = 1.8, 95% CI = 1.2-2.7, P = .004).Conclusion:Our results show a preference of distinct BCC subtypes for certain anatomical locations.