Details

Autor(en) / Beteiligte

• Vorob'eva, T M
• Berchenko, O G
• Geiko, V V
• Kolyadko, S P
• Bevzyuk, D A
• Pan, I R
• Epstein, O I

Titel

Effect of potentiated antibodies to morphine on behavioral reactions in rats with morphine dependence

Ist Teil von

• Bulletin of experimental biology and medicine, 2003, Vol.135 Suppl 7, p.34

Ort / Verlag

United States: Springer Nature B.V

Erscheinungsjahr

2003

Quelle

MEDLINE

Beschreibungen/Notizen

• We studied the effect of potentiated antibodies to morphine (10(-100) wt %) on self-stimulation of the lateral hypothalamus and behavioral reactions reflecting the severity of withdrawal syndrome in rats with morphine dependence. Repeated treatment with potentiated antibodies to morphine increased the rate of self-stimulation, suppressed active avoidance response, promoted freezing behavior after acoustic stimulation, and decreased tail-flick latency in rats after morphine withdrawal. Distilled water did not produce these changes.