Details

Autor(en) / Beteiligte

• Vitinius, F.
• Reklat, A.
• Hellmich, M.
• Klask, E.
• Wahlers, T.
• Rahmanian, P.B.
• Pfister, R.
• Müller-Ehmsen, J.
• Albus, C.

Titel

Pretransplant Psychosocial Functioning Predicts Survival of Patients on Waiting List for Heart Transplantation - Results of a Prospective Study

Ist Teil von

• Journal of psychosomatic research, 2018-06, Vol.109, p.143-143

Ort / Verlag

London: Elsevier Inc

Erscheinungsjahr

2018

Quelle

Applied Social Sciences Index & Abstracts (ASSIA)

Beschreibungen/Notizen

• Aims: Only few studies have focused on the interaction between pretransplant psychological variables and adherence to therapy after heart transplantation (HTx). The objective of this study is to identify psychological predictors of nonadherence and survival. Methods: Patients listed for HTx were evaluated before (t0), immediately after HTx (t1) and 6 months thereafter (t2). Psychosocial functioning was measured by the Transplant Evaluation Rating Scale (TERS). Depression and anxiety were assessed by Patient Health Questionnaire (PHQ-D) and the Hospital Anxiety and Depression Scale (HADS-D). Barriers to immunosuppressive adherence post-HTx by the Medication Experience Scale for Immunosuppressants (MESI). Results: 50 patients were evaluated pre-HTx and 14 patients after HTx. There was a moderate correlation between the TERS and depression at t0 (r = 0.53, p<0.001). Results of the TERS (t0) and the MESI (T2) showed a strong correlation (r = 0.84, p<0.001). According to the TERS, the patients were divided into three risk groups. Compared with inconspicuous patients (n=23), risk patients (n=21) and patients with concern (n=6) demonstrated a higher mortality (Kaplan-Meier curve) and raised MESI values. Conclusion: These results suggest that the TERS may be a powerful predictor for survival. There is need for further longitudinal data which may confirm our results including a larger sample size.