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Recent Developments in the C(sp3)−H Functionalization of 2‐Oxindoles through Radical Reactions
Ist Teil von
Asian journal of organic chemistry, 2018-08, Vol.7 (8), p.1429-1438
Ort / Verlag
Weinheim: Wiley Subscription Services, Inc
Erscheinungsjahr
2018
Quelle
Wiley Online Library All Journals
Beschreibungen/Notizen
3‐Substituted 2‐oxindoles are prevalent in a variety of natural products and bioactive compounds. As such, the synthesis of these molecules is highly desirable. This Focus Review provides a critical overview of recent developments (in particular, reports since 2013) in the C(sp3)−H functionalization of 2‐oxindoles through radical reactions. The main achievements in this field are presented according to the bonds that are formed. Special attention is paid to the reaction mechanisms, and a personal outlook on future developments in this research area is provided.
The New Radicals: 3‐Substituted 2‐oxindoles are prevalent in a variety of natural products and bioactive compounds. This Focus Review provides a critical overview of recent developments in the C(sp3)−H functionalization of 2‐oxindoles through radical reactions.