Details

Autor(en) / Beteiligte

• Wei, Chih‐Ming
• Chen, Huey‐Ling
• Lee, Ping‐Ing
• Chen, Chong‐Ming
• Ma, Chun‐Yi
• Hwu, Wuh‐Liang

Titel

Reye's syndrome developing in an infant on treatment of Kawasaki syndrome

Ist Teil von

• Journal of paediatrics and child health, 2005-05, Vol.41 (5‐6), p.303-304

Ort / Verlag

PO Box 378 , Carlton South Victoria 3053 , Australia: Blackwell Science Pty

Erscheinungsjahr

2005

Quelle

Wiley Blackwell Single Titles

Beschreibungen/Notizen

• :  Aspirin is commonly used as an anti‐inflammatory therapy for Kawasaki syndrome. Early initiation with high dose aspirin (80 to >100 mg/kg per day), followed by low‐dose therapy at the afebrile stage, has been often used to reduce morbidity and mortality in coronary complications. We report a 10‐month‐old infant who was diagnosed with Kawasaki syndrome. Sudden onset of poor activity, poor appetite, lethargy, tachycardia, tachypnea, hepatomegaly, increased AST/ALT, coagulopathy and hyperammonemia developed 3 days after the high‐dose aspirin therapy. His histopathological and ultrastructural findings from the liver biopsy were compatible with Reye's syndrome. He recovered completely, and there was no recurrence.