Details

Autor(en) / Beteiligte

• Liu, Wei
• Ding, Fang
• Wang, Yanying
• Mao, Lei
• Liang, Ruoxuan
• Zou, Ping
• Wang, Xianxiang
• Zhao, Qingbiao
• Rao, Hanbing

Titel

Fluorometric and colorimetric sensor array for discrimination of glucose using enzymatic-triggered dual-signal system consisting of Au@Ag nanoparticles and carbon nanodots

Ist Teil von

• Sensors and actuators. B, Chemical, 2018-07, Vol.265, p.310-317

Ort / Verlag

Lausanne: Elsevier B.V

Erscheinungsjahr

2018

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• [Display omitted] The fluorescent of carbon nanodots (C-dots) was quenched by Au@Ag bimetallic core-shell nanoparticles (Au@Ag NPs), Hydrogen peroxide (H2O2) produced by the enzymatic-triggered oxidation of glucose, in the presence of H2O2, the silver shell of Au@Ag NPs was etched and turn into Ag+, as a result, the fluorescent of C-dots was recovery and the color of Au@Ag NPs was change. Thus, a dual-signal senor was established for glucose detection. •Au@Ag NPs was synthesized by facile one-pot synthesis with sodium citrate as reducing agent.•A dual-signal senor was established for glucose detection based on Au@Ag NPs and C-dots.•The strategy has wide linear range and low detection limit for glucose detection.•The proposed strategy demonstrated good potential for detecting glucose in blood samples. In the present study, a dual-signal senor for glucose detection has been established based on Au@Ag bimetallic core-shell nanoparticles (Au@Ag NPs) and carbon nanodots (C-dots). As a donor of surface plasmon-enhanced energy transfer (SPEET) in this senor, the fluorescence of C-dots was quenched by silver shell (acceptor) of the Au@Ag NPs. Furthermore, Au@Ag NPs serve as colorimetric reporter for the etching effect of H2O2 produced from enzymatic-triggered oxidation of glucose on silver shell, the fluorescence of C-dots recovery. Therefore, the change of color and fluorescence of this senor are directly related to the concentration of glucose. The linear relationship between fluorescence (absorbance) intensity and glucose was in the range of 2.0–400 μM (0.50–300 μM) with a low limit of detection of 0.67 μM (0.20 μM). Besides, this dual-signal senor also exhibited excellent selectivity for distinguishing glucose from common substances. This sensor system was successfully applied to the analysis of glucose in pretreated blood sample with satisfactory results, demonstrating the application prospect for practical sample analysis.