Details

Autor(en) / Beteiligte

• Kaiser, Anna-Maria
• Kempker, Lena
• Neiger, Reto

Titel

Parathyroid immunohistochemistry in a 12-year-old mixed-breed dog with parathyroid adenocarcinoma

Ist Teil von

• Veterinary record case reports, 2018-07, Vol.6 (3), p.e000601-n/a

Ort / Verlag

London: British Veterinary Association

Erscheinungsjahr

2018

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• SummaryA 12-year-old, female, spayed, mixed-breed dog with acute lethargy, anorexia and weakness and markedly elevated total and ionised calcium concentration showed an enlarged left cranial parathyroid gland on ultrasonography of the ventral neck. Despite preoperative therapy with furosemide and calcitonin, there was no decline of plasma ionised calcium concentration. The dog deteriorated rapidly and was euthanased two days after initial presentation. Postmortem histopathology revealed parathyroid tissue with characteristics of malignancy as local and vascular invasion. Immunohistochemistry showed parathyroid hormone positive staining of these cells. Unusual clinical presentation and histopathological characteristics are discussed.