Details

Autor(en) / Beteiligte

• Gekas, Jean
• Gagné, Geneviève
• Bujold, Emmanuel
• Douillard, Danie
• est, Jean-CLaude
• Reinharz, Daniel
• Rousseau, François

Titel

Comparison of different strategies in prenatal screening for Down's syndrome: cost effectiveness analysis of computer simulation

Ist Teil von

• BMJ. British medical journal (International ed.), 2009-02, Vol.338 (7692), p.453

Auflage

International edition

Ort / Verlag

London: BMJ Publishing Group

Erscheinungsjahr

2009

Quelle

Applied Social Sciences Index & Abstracts (ASSIA)

Beschreibungen/Notizen

• Major advances have been made in prenatal screening for Down's syndrome, but there is still no consensus on the most cost effective alternative to using maternal age alone as a screening strategy, and no national strategy exists in the United States or Canada. Here, Gekas et al assess and compare the cost effectiveness of three different strategies for prenatal screening for Down's syndrome (integrated test, sequential screening, and contingent screenings) and determine the most useful cut-off values for risk. They conclude that contingent screening, with a first trimester cut-off value for high risk of 1 in 9, is the preferred option for prenatal screening of women for pregnancies affected by Down's syndrome.