Details

Autor(en) / Beteiligte

• Vickers, Andrew J
• Altman, Douglas G

Titel

Analysing controlled trials with baseline and follow up measurements

Ist Teil von

• BMJ. British medical journal (International ed.), 2001-11, Vol.323 (7321), p.1123

Auflage

International edition

Ort / Verlag

London: BMJ Publishing Group

Erscheinungsjahr

2001

Link zum Volltext

Quelle

Applied Social Sciences Index & Abstracts (ASSIA)

Beschreibungen/Notizen

• Some use change scores to take account of chance imbalances at baseline between the treatment groups. However, analysing change does not control for baseline imbalance because of regression to the mean1 2: baseline values are negatively correlated with change because patients with low scores at baseline generally improve more than those with high scores.