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Wave-induced seabed instability is an important problem considered by ocean engineers. On basis of analyzing the present calculation methods for wave-induced seabed sliding instability, a new method , referred to the overall stress state method, is established to calculate the seabed sliding stability under wave loading. The new method has been compared with others, and the wave-induced sliding failure characteristics of sandy seabed and the soft clay one has been analyzed. The results have shown that the overall stress state method is applicable to compute the seabed sliding instability. For sandy seabed, saturation has great influence on its sliding instability, and the sliding depth will reach the maximum when the seabed thickness is 0.2 times of the wave length. For homogeneous soft clay seabed with slope angle no larger than 2° under wave loading, location of the most dangerous sliding surface is only related with the wave length, that is, the sliding depth is 0.21 times of the wave length and the half c