The New England journal of medicine, 2018-03, Vol.378 (11), p.1004-1017
- Molloy, Síle F
- Kanyama, Cecilia
- Heyderman, Robert S
- Loyse, Angela
- Kouanfack, Charles
- Chanda, Duncan
- Mfinanga, Sayoki
- Temfack, Elvis
- Lakhi, Shabir
- Lesikari, Sokoine
- Chan, Adrienne K
- Stone, Neil
- Kalata, Newton
- Karunaharan, Natasha
- Gaskell, Kate
- Peirse, Mary
- Ellis, Jayne
- Chawinga, Chimwemwe
- Lontsi, Sandrine
- Ndong, Jean-Gilbert
- Bright, Philip
- Lupiya, Duncan
- Chen, Tao
- Bradley, John
- Adams, Jack
- van der Horst, Charles
- van Oosterhout, Joep J
- Sini, Victor
- Mapoure, Yacouba N
- Mwaba, Peter
- Bicanic, Tihana
- Lalloo, David G
- Wang, Duolao
- Hosseinipour, Mina C
- Lortholary, Olivier
- Jaffar, Shabbar
- Harrison, Thomas S
2018
Details
- Autor(en) / Beteiligte
- Molloy, Síle F
- Kanyama, Cecilia
- Heyderman, Robert S
- Loyse, Angela
- Kouanfack, Charles
- Chanda, Duncan
- Mfinanga, Sayoki
- Temfack, Elvis
- Lakhi, Shabir
- Lesikari, Sokoine
- Chan, Adrienne K
- Stone, Neil
- Kalata, Newton
- Karunaharan, Natasha
- Gaskell, Kate
- Peirse, Mary
- Ellis, Jayne
- Chawinga, Chimwemwe
- Lontsi, Sandrine
- Ndong, Jean-Gilbert
- Bright, Philip
- Lupiya, Duncan
- Chen, Tao
- Bradley, John
- Adams, Jack
- van der Horst, Charles
- van Oosterhout, Joep J
- Sini, Victor
- Mapoure, Yacouba N
- Mwaba, Peter
- Bicanic, Tihana
- Lalloo, David G
- Wang, Duolao
- Hosseinipour, Mina C
- Lortholary, Olivier
- Jaffar, Shabbar
- Harrison, Thomas S
- Titel
- Antifungal Combinations for Treatment of Cryptococcal Meningitis in Africa
- Ist Teil von
- The New England journal of medicine, 2018-03, Vol.378 (11), p.1004-1017
- Ort / Verlag
- United States: Massachusetts Medical Society
- Erscheinungsjahr
- 2018
- Link zum Volltext
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Globally, cryptococcal meningitis is a leading cause of mortality among people with AIDS, despite the availability of effective amphotericin B–based therapy. In this trial in sub-Saharan Africa, the efficacy of two simpler treatment regimens was assessed.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0028-4793eISSN: 1533-4406DOI: 10.1056/NEJMoa1710922Titel-ID: cdi_proquest_journals_2023003130
- Format
- –
- Schlagworte
- Administration, Oral, Adult, Africa - epidemiology, AIDS-Related Opportunistic Infections - drug therapy, Amphotericin B, Amphotericin B - administration & dosage, Amphotericin B - adverse effects, Analysis, Antifungal agents, Antifungal Agents - adverse effects, Antifungal Agents - therapeutic use, Antigens, Arid zones, Body weight, Care and treatment, Clinical trials, Cryptococcal meningitis, Dosage and administration, Drug Administration Schedule, Drug dosages, Drug Therapy, Combination, Fatalities, Female, Fluconazole, Fluconazole - administration & dosage, Fluconazole - adverse effects, Flucytosine, Flucytosine - administration & dosage, Flucytosine - adverse effects, Health risk assessment, HIV, HIV Seropositivity - complications, Human immunodeficiency virus, Humans, Induction therapy, Infections, Infectious diseases, Kaplan-Meier Estimate, Laboratories, Male, Medical research, Medicine, Meningitis, Meningitis, Cryptococcal - drug therapy, Meningitis, Cryptococcal - mortality, Mortality, Patients, Proportional Hazards Models, Teaching hospitals, Treatment outcome