Proceedings of the National Academy of Sciences - PNAS, 1992-10, Vol.89 (19), p.8948-8952
1992
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Details
- Autor(en) / Beteiligte
- Titel
- Spatial Pattern of Receptor Expression in the Olfactory Epithelium
- Ist Teil von
- Proceedings of the National Academy of Sciences - PNAS, 1992-10, Vol.89 (19), p.8948-8952
- Ort / Verlag
- Washington, DC: National Academy of Sciences of the United States of America
- Erscheinungsjahr
- 1992
- Quelle
- Free E-Journal (出版社公開部分のみ）
- Beschreibungen/Notizen
- A PCR-based strategy for amplifying putative receptors involved in murine olfaction was employed to isolate a member (OR3) of the seven-transmembrane-domain receptor superfamily. During development, the first cells that express OR3 appear adjacent to the wall of the telencephalic vesicle at embryonic day 10. The OR3 receptor is uniquely expressed in a subset of olfactory cells that have a characteristic bilateral symmetry in the adult olfactory epithelium. This receptor and its specific pattern of expression may serve a functional role in odor coding or, alternatively, may play a role in the development of the olfactory system.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0027-8424eISSN: 1091-6490DOI: 10.1073/pnas.89.19.8948Titel-ID: cdi_proquest_journals_201265795
- Format
- –
- Schlagworte
- Amino Acid Sequence, Amino acids, Animals, Antisense Elements (Genetics), Biological and medical sciences, Cellular biology, Central nervous system, developmental stages, DNA, DNA - genetics, DNA - isolation & purification, Embryo, Mammalian, Embryology: invertebrates and vertebrates. Teratology, Epithelial Cells, Epithelium, Epithelium - physiology, Fundamental and applied biological sciences. Psychology, Genomic Library, Genomics, In Situ Hybridization, Mice, Molecular embryology, Molecular Sequence Data, Neurons, Nose, olfactory epithelium, Olfactory Pathways - cytology, Olfactory Pathways - physiology, olfactory receptors, patterns, Polymerase chain reaction, Polymerase Chain Reaction - methods, Protein Conformation, Proteins, Receptors, Receptors, Neurotransmitter - genetics, Receptors, Odorant, Restriction Mapping, RNA, RNA - genetics, RNA - isolation & purification, RNA, Antisense, RNA, Messenger - analysis, RNA, Messenger - genetics, Smell