UNIVERSI
TÄ
TS-
BIBLIOTHEK
P
ADERBORN
Anmelden
Menü
Menü
Start
Hilfe
Blog
Weitere Dienste
Neuerwerbungslisten
Fachsystematik Bücher
Erwerbungsvorschlag
Bestellung aus dem Magazin
Fernleihe
Einstellungen
Sprache
Deutsch
Deutsch
Englisch
Farbschema
Hell
Dunkel
Automatisch
Sie befinden Sich nicht im Netzwerk der Universität Paderborn. Der Zugriff auf elektronische Ressourcen ist
gegebenenfalls
nur via VPN oder Shibboleth (DFN-AAI) möglich.
mehr Informationen...
Universitätsbibliothek
Katalog
Suche
Details
Zur Ergebnisliste
Ergebnis 21 von 39
Datensatz exportieren als...
BibTeX
Pleurotus sajor‐caju can be used to synthesize silver nanoparticles with antifungal activity against Candida albicans
Journal of the science of food and agriculture, 2018-02, Vol.98 (3), p.1197-1207
Musa, Siti Fadhilah
Yeat, Ting Seng
Kamal, Laina Zarisa Mohd
Tabana, Yasser M
Ahmed, Mowaffaq Adam
El Ouweini, Ahmad
Lim, Vuanghao
Keong, Lee Chee
Sandai, Doblin
2018
Details
Autor(en) / Beteiligte
Musa, Siti Fadhilah
Yeat, Ting Seng
Kamal, Laina Zarisa Mohd
Tabana, Yasser M
Ahmed, Mowaffaq Adam
El Ouweini, Ahmad
Lim, Vuanghao
Keong, Lee Chee
Sandai, Doblin
Titel
Pleurotus sajor‐caju can be used to synthesize silver nanoparticles with antifungal activity against Candida albicans
Ist Teil von
Journal of the science of food and agriculture, 2018-02, Vol.98 (3), p.1197-1207
Ort / Verlag
Chichester, UK: John Wiley & Sons, Ltd
Erscheinungsjahr
2018
Link zum Volltext
Quelle
Wiley Online Library Journals Frontfile Complete
Beschreibungen/Notizen
BACKGROUND Green synthesis of silver nanoparticles (AgNPs) has become widely practiced worldwide. In this study, AgNPs were synthesized using a hot‐water extract of the edible mushroom Pleurotus sajor‐caju. The product, PSC‐AgNPs, was characterized by using UV–visible spectra, dynamic light scattering analysis, transmission electron microscopy (TEM), X‐ray diffraction (XRD) and Fourier transform infrared (FTIR) spectrometry. To assess its antifungal activity against Candida albicans, gene transcription and protein expression analyses were conducted for CaICL1 and its product, ICL, using real‐time quantitative polymerase chain reaction and western blot, respectively. RESULTS PSC‐AgNPs with an average particle size of 11.68 nm inhibited the growth of the pathogenic yeast C. albicans. Values for minimum inhibitory concentration and minimum fungicidal concentration were 250 and 500 mg L−1, respectively. TEM images revealed that the average particle size of PSC‐AgNPs was 16.8 nm, with the values for zeta potential and the polydispersity index being −8.54 mV and 0.137, respectively. XRD and FTIR spectra showed PSC‐AgNPs to have a face‐centered cubic crystalline structure. The polysaccharides and amino acid residues present in P. sajor‐caju extract were found to be involved in reducing Ag+ to AgNP. Both CaICL1 transcription and ICL protein expression were found to be suppressed in the cells treated with PSC‐AgNPs as compared with the control. CONCLUSION Our PSC‐AgNP preparation makes for a promising antifungal agent that can downregulate isocitrate lyase. © 2017 Society of Chemical Industry
Sprache
Englisch
Identifikatoren
ISSN: 0022-5142
eISSN: 1097-0010
DOI: 10.1002/jsfa.8573
Titel-ID: cdi_proquest_journals_1985925880
Format
–
Schlagworte
Amino acids
,
Antifungal activity
,
Antifungal Agents - chemistry
,
Antifungal Agents - metabolism
,
Antifungal Agents - pharmacology
,
Candida albicans
,
Candida albicans - drug effects
,
Candida albicans - growth & development
,
Electron microscopy
,
Fourier transforms
,
Fungicides
,
Gene expression
,
Green Chemistry Technology
,
Infrared spectroscopy
,
Isocitrate lyase
,
Light diffraction
,
Light scattering
,
Metal Nanoparticles - chemistry
,
Microbial Sensitivity Tests
,
Microscopy, Electron, Transmission
,
Microstructure
,
Minimum inhibitory concentration
,
mRNA, proteomics
,
Nanoparticles
,
Particle Size
,
Photon correlation spectroscopy
,
Plant Extracts - chemistry
,
Plant Extracts - metabolism
,
Pleurotus - chemistry
,
Pleurotus - metabolism
,
Pleurotus sajor-caju
,
Polydispersity
,
Polymerase chain reaction
,
Polysaccharides
,
Protein expression
,
Saccharides
,
Silver
,
Silver - chemistry
,
Silver - metabolism
,
Silver - pharmacology
,
silver nanoparticles
,
Spectrometry
,
Synthesis
,
Transcription
,
Transmission electron microscopy
,
Ultraviolet radiation
,
X-ray diffraction
,
Yeast
,
Zeta potential
Weiterführende Literatur
Empfehlungen zum selben Thema automatisch vorgeschlagen von
bX