Details

Autor(en) / Beteiligte

• Boffetta, P.
• Tubiana, M.
• Hill, C.
• Boniol, M.
• Aurengo, A.
• Masse, R.
• Valleron, A.-J.
• Monier, R.
• de Thé, G.
• Boyle, P.
• Autier, P.

Titel

The causes of cancer in France

Ist Teil von

• Annals of oncology, 2009-03, Vol.20 (3), p.550-555

Ort / Verlag

Oxford: Oxford University Press

Erscheinungsjahr

2009

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• Background: While external factors are responsible for many human cancers, precise estimates of the contribution of known carcinogens to the cancer burden in a given population have been scarce. Methods: We estimated the proportion of cancer deaths which occurred in France in 2000 attributable to known risk factors, based on data on frequency of exposure around 1985. Results: In 2000, tobacco smoking was responsible for 23.9% of cancer deaths (33.4% in men and 9.6% in women), alcohol drinking for 6.9% (9.4% in men and 3.0% in women) and chronic infections for 3.7%. Occupation is responsible for 3.7% of cancer deaths in men; lack of physical activity, overweight/obesity and use of exogenous hormones are responsible for 2%–3% of cancer deaths in women. Other risk factors, including pollutants, are responsible for <1% of cancer deaths. Thus, known risk factors explain 35.0% of cancer deaths, and 15.0% among never smokers. Conclusions: While cancer mortality is decreasing in France, known risk factors of cancer explain only a minority of cancers, with a predominant role of tobacco smoking.