Details

Autor(en) / Beteiligte

• Peralta, Sonia Luque
• de Carvalho, Pedro Henrique Azambuja
• Ccahuana-Vásquez, Renzo Alberto
• de Pereira, Claudio Martin Pereira
• Cury, Jaime Aparecido
• Piva, Evandro
• Lund, Rafael G.

Titel

Cytotoxicity, genotoxicity and antibiofilm activity on Streptococcus mutans of an experimental self-etching adhesive system containing natural Butia capitata oil

Ist Teil von

• International journal of adhesion and adhesives, 2017-10, Vol.78, p.95-101

Ort / Verlag

Kidlington: Elsevier Ltd

Erscheinungsjahr

2017

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• This study evaluated the biocompatibility and antibiofilm effects on Streptococcus mutans of an experimental self-etching adhesive system formulated with a natural vegetable product. The cytotoxicity of Clearfil Protect Bond (CPB), Clearfil SE Bond (CSEB), Adper SE Plus (AP), an experimental adhesive containing Butia capitata oil (EA) and an oil-free experimental adhesive as control (CA) was tested on 3T3/NIH mouse fibroblasts. Genotoxicity was indicated by micronuclei formation, and cell alterations were analyzed using light microscopy. To evaluate the effect of the adhesives on S. mutans biofilm, biomass samples were collected for dry weight and bacterial viability analyses, and the pH of the culture media was determined daily as an indicator of biofilm acidogenicity. The CA primer and EA uncured bond adhesive were the least toxic. No statistical difference was observed between EA and the untreated control, and EA showed similar effect to CPB. These findings suggest EA is biocompatible and presents activity against S. mutans biofilm.