The New England journal of medicine, 2017-09, Vol.377 (10), p.936-946
2017
Volltextzugriff (PDF)
Details
- Autor(en) / Beteiligte
- Titel
- Tezepelumab in Adults with Uncontrolled Asthma
- Ist Teil von
- The New England journal of medicine, 2017-09, Vol.377 (10), p.936-946
- Ort / Verlag
- United States: Massachusetts Medical Society
- Erscheinungsjahr
- 2017
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Treatment with tezepelumab, a human monoclonal antibody specific for thymic stromal lymphopoietin, reduced exacerbation frequency among patients whose asthma remained uncontrolled with long-acting beta-agonists and medium-to-high doses of inhaled glucocorticoids.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0028-4793eISSN: 1533-4406DOI: 10.1056/NEJMoa1704064Titel-ID: cdi_proquest_journals_1936273479
- Format
- –
- Schlagworte
- Administration, Inhalation, Adrenergic beta-Agonists - therapeutic use, Adult, Anti-Asthmatic Agents - therapeutic use, Antibodies, Monoclonal - administration & dosage, Antibodies, Monoclonal - adverse effects, Antibodies, Monoclonal, Humanized, Antigens, Asthma, Asthma - drug therapy, Asthma - immunology, Cytokines, Cytokines - immunology, Dose-Response Relationship, Drug, Double-Blind Method, Drug Therapy, Combination, Eosinophils, Female, Glucocorticoids, Glucocorticoids - therapeutic use, Humans, Inflammation, Injections, Subcutaneous, Intention to Treat Analysis, Leukocytes (eosinophilic), Male, Middle Aged, Monoclonal antibodies, Quality of life, Respiratory therapy, Thymic stromal lymphopoietin, Thymus