Natural product research, 2017-04, Vol.31 (8), p.918-924
2017
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Details
- Autor(en) / Beteiligte
- Titel
- Furofuran lignan glucosides from the leaves of Vitex negundo var. cannabifolia
- Ist Teil von
- Natural product research, 2017-04, Vol.31 (8), p.918-924
- Ort / Verlag
- England: Taylor & Francis
- Erscheinungsjahr
- 2017
- Quelle
- Taylor & Francis
- Beschreibungen/Notizen
- Two new furofuran lignan glucosides, cannabilignin (1) and isocannabilignin (2), together with four known compounds (3-6), were isolated from the leaves of Vitex negundo var. cannabifolia. The structures of the isolates were elucidated by analysis of spectroscopic data. Compound 3 exhibited weak inhibition of nitric oxide production in lipopolysaccharide-stimulated BV-2 microglial cells with IC 50 value of 69.1 ± 5.8 μM.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1478-6419eISSN: 1478-6427DOI: 10.1080/14786419.2016.1255887Titel-ID: cdi_proquest_journals_1923054943
- Format
- –
- Schlagworte
- Animals, Cell Line, Data processing, Drug Evaluation, Preclinical - methods, Glucosides, Glucosides - chemistry, Glucosides - isolation & purification, Glucosides - pharmacology, Inhibitory Concentration 50, Leaves, lignan glucoside, Lignans - chemistry, Lignans - pharmacology, Lipopolysaccharides, Lipopolysaccharides - pharmacology, Mice, Microglia - drug effects, Microglia - metabolism, Microglial cells, Molecular Structure, Nitric oxide, Nitric Oxide - biosynthesis, Plant Leaves - chemistry, Spectroscopic analysis, Verbenaceae, Vitex - chemistry, Vitex negundo, Vitex negundo var. cannabifolia