Details

Autor(en) / Beteiligte

• Zhou, Xukai
• Qi, Zisong
• Yu, Songjie
• Kong, Lingheng
• Li, Yang
• Tian, Wan‐Fa
• Li, Xingwei

Titel

Synthesis of 2‐Substituted Quinolines via Rhodium(III)‐Catalyzed C–H Activation of Imidamides and Coupling with Cyclopropanols

Ist Teil von

• Advanced synthesis & catalysis, 2017-05, Vol.359 (10), p.1620-1625

Ort / Verlag

Heidelberg: Wiley Subscription Services, Inc

Erscheinungsjahr

2017

Quelle

Wiley-Blackwell Journals

Beschreibungen/Notizen

• An efficient synthesis of 2‐substituted quinolines from readily available cyclopropanols and imidamides has been developed, where the cyclopropanol acts as a C3 synthon. With the assistance of a bifunctional imidamide directing group, the reaction occurred via sequential C–H/C–C cleavage and C–C/C–N bond formation.