Details

Autor(en) / Beteiligte

• Xing, Zi‐Min
• Song, Le‐Le
• Li, Feng‐Xing
• Xu, Nian‐Sheng
• Wang, Lu‐Feng
• Shi, Zi‐Fa
• Cao, Xiao‐Ping

Titel

Organocatalytic Enantioselective Tandem Michael Addition and Cyclization Reaction of Trisubstituted 2‐Nitro‐1,3‐enynes with Cyclic 1,3‐Diketones

Ist Teil von

• Advanced synthesis & catalysis, 2017-06, Vol.359 (11), p.1892-1900

Ort / Verlag

Heidelberg: Wiley Subscription Services, Inc

Erscheinungsjahr

2017

Quelle

Wiley Online Library

Beschreibungen/Notizen

• An enantioselective tandem Michael addition/cyclization reaction between trisubstituted 2‐nitro‐1,3‐enynes and cyclic 1,3‐diketones catalyzed by a chiral organosquaramide catalyst in the presence of Ag2CO3 was developed. The chiral functionalized chromene products could be obtained in good yield and in 80–99% enantiomeric excess. The structures and absolute configurations of some of the products were confirmed by X‐ray crystallographic analysis.