Details

Autor(en) / Beteiligte

• Wang, Xue-Mei
• Wang, Xi-Cun
• Wang, Chen-Fei
• Yang, Liang

Titel

One-pot synthesis of 4-aryl-7,7-dimethyl-5-oxo-3,4,5,6,7,8-hexahydrocoumarin derivatives in glycerol

Ist Teil von

• Green chemistry letters and reviews, 2017-07, Vol.10 (3), p.134-137

Ort / Verlag

Abingdon: Taylor & Francis

Erscheinungsjahr

2017

Link zum Volltext

Quelle

Taylor & Francis Journals Auto-Holdings Collection

Beschreibungen/Notizen

• Glycerol is a new green organic solvent. It not only acts as a phase transfer catalyst but also as a recyclable solvent by significantly enhancing the intramolecular cyclization. A series of 4-aryl-7,7 -dimethyl-5-oxo-3,4,5,6,7,8-hexahydrocoumarin derivatives were synthesized by one-pot multicomponent reaction of Meldrum's acid with benzaldehyde, and cyclohexanedione in glycerol. Compared to classic methods, this method has the advantages of milder reaction conditions, good yields, easy processing and environmental benignity.