Details

Autor(en) / Beteiligte

• Vignesh, Arumugam
• Kaminsky, Werner
• Dharmaraj, Nallasamy

Titel

Arylation of N‐Methyl‐2‐oxindole with Arylboronic Acids in Water Catalyzed by Palladium(II) Pincer Complexes with a Low Catalyst Loading

Ist Teil von

• ChemCatChem, 2017-03, Vol.9 (6), p.910-914

Ort / Verlag

Weinheim: Wiley Subscription Services, Inc

Erscheinungsjahr

2017

Quelle

Wiley Blackwell Single Titles

Beschreibungen/Notizen

• Two new PdII ONO pincer complexes were utilized efficiently as homogeneous catalysts for the site‐selective C3‐arylation of N‐methyl‐2‐oxindole with arylboronic acids at room temperature in aqueous media to yield a series of 3‐aryl‐N‐methyl‐2‐oxindoles. This catalytic reaction progressed well with a low catalyst loading (0.01 mol %) under open‐flask conditions. Notably, a column‐chromatography‐free method for the quantitative preparation of C3‐arylated N‐methyl‐2‐oxindoles is reported. The catalyst showed good compatibility with wide range of substrates with recyclability in up to five consecutive runs without an appreciable loss of yield. Power of palladium pincer complex: Two new PdII ONO pincer complexes are utilized efficiently as homogeneous catalysts for the site‐selective C3‐arylation of N‐methyl‐2‐oxindole with arylboronic acids at room temperature in aqueous media to yield a series of 3‐aryl‐N‐methyl‐2‐oxindoles.