Details

Autor(en) / Beteiligte

• Vignesh, Arumugam
• Kaminsky, Werner
• Dharmaraj, Nallasamy

Titel

Expeditious Assembly of Fluorenones through Domino Reactions of Benzoyl Chlorides with Arylboronic Acids Catalyzed by ONO Pincer-like Palladium(II) Complexes

Ist Teil von

• ChemCatChem, 2016-10, Vol.8 (20), p.3207-3212

Ort / Verlag

Weinheim: Blackwell Publishing Ltd

Erscheinungsjahr

2016

Quelle

Wiley-Blackwell Journals

Beschreibungen/Notizen

• A new set of palladium(II) complexes featuring ONO pincer‐type ligands were synthesized and utilized as efficient homogeneous catalysts for the domino reactions of benzoyl chlorides with arylboronic acids to yield a library of fluorenones. The titled reaction proceeded smoothly in H2O/MeOH media at a low catalyst loading (0.1 mol %) under mild reaction conditions in an open flask, and the catalyst could be reused over six consecutive runs. To validate the currently developed methodology for industrial‐level applications, a gram‐scale synthesis was done. Advantageously, the present protocol does not require any external oxidant, additives, or phase‐transfer agents. Let′s play DomONOes! PdII complexes featuring ONO pincer‐type ligands are synthesized and utilized as efficient homogeneous catalysts for the domino reactions of benzoyl chlorides with arylboronic acids to yield a library of fluorenones. The reaction proceeds smoothly in H2O/MeOH media at a catalyst loading of 0.1 mol % under mild reaction conditions in an open flask, and the catalyst can be reused over six consecutive runs.