Details

Autor(en) / Beteiligte

• Scalise, Valentina
• Balia, Cristina
• Cianchetti, Silvana
• Carnicelli, Vittoria
• Faita, Francesca
• Neri, Tommaso
• Zucchi, Riccardo
• Corti, Alessandro
• Celi, Alessandro
• Pedrinelli, Roberto

Titel

HIGH GLUCOSE INCREASES GAMMA-GLUTAMYLTRANSFERASE-INDUCED TISSUE FACTOR EXPRESSION IN HUMAN PERIPHERAL BLOOD MONONUCLEAR CELLS

Ist Teil von

• Journal of the American College of Cardiology, 2016-04, Vol.67 (13), p.594-594

Ort / Verlag

New York: Elsevier Inc

Erscheinungsjahr

2016

Quelle

ScienceDirect Journals (5 years ago - present)

Beschreibungen/Notizen

• Methods Human peripheral blood mononuclear cells obtained from healthy donors (discontinuous Ficoll/Hystopaque density gradient) were incubated with GGT (0.5ng/µl) either alone or with anti-GGT antibody (2.5µg/ml). Because of the pivotal role played by NFkB, a redox-sensitive transcription factor encoding TF, we also evaluated the effect NF-κB inhibition by BAY-11-7082 (10-5M) and N-acetylcysteine (10-3M), an antioxidant.