Details

Autor(en) / Beteiligte

• Maurer, Mathew S
• Ginns, Jonathan
• Maron, Barry
• Olivotto, Iacopo
• Lesser, John
• Gruner, Christiane
• Crean, Andrew
• Rakowski, Harry
• Rowin, Ethan
• Lombardi, Massimo
• Spirito, Paolo
• Biagini, Elena
• Autore, Camillo
• Manning, Warren
• Tomberli, Benedetta
• Maron, Martin
• Chan, Raymond

Titel

THE MYOCARDIAL CONTRACTION FRACTION (MCF) IS ASSOCIATED WITH NYHA CLASS AS WELL AS DELAYED ENHANCEMENT BY CARDIAC MRI IN HYPERTROPHIC CARDIOMYOPATHY AND PREDICTS SUDDEN CARDIAC DEATH

Ist Teil von

• Journal of the American College of Cardiology, 2016-04, Vol.67 (13), p.1508-1508

Ort / Verlag

New York: Elsevier Inc

Erscheinungsjahr

2016

Link zum Volltext

Quelle

EZB Electronic Journals Library

Beschreibungen/Notizen

• Age (years) 46.4±17.0 47.1±16.7 46.1±16.6 45.8±17.9 46.8±17.0 NS* Gender (male) 815 (63%) 217 (67%) 222 (69%) 203 (63%) 173 (53%) 0.0001* NYHA class 1.58±0.74 1.73±0.80 1.61±0.76 1.52±0.72 1.46±0.65 <0.001* LVOT gradient (mm Hg) 19.3±31.4 24.0±33.8 20.0±35.0 18.9±30.5 14.1±24.9 0.01* LVOT gradient >30mmHG 317 (25%) 100 (31%) 76 (23%) 85 (26%) 56 (17%) 0.006* Mean Risk Factors 0.47±0.65 0.62±0.72 0.47±0.66 0.39±0.58 0.41±0.60 <0.001* NSVT 204 65 (20%) 60 (19%) 46 (14%) 33 (10%) 0.003* Syncope 122 35 (11%) 30 (9%) 27 (8%) 30 (9%) NS* Maximum thickness >30 mm 68 53 (16%) 9 (3%) 4 (1%) 2 (0.6%) <0.0001* CMR parametersLV EDV (ml)LV ESV (ml)LV SV (ml)EF (%)Mass (grams) % Delayed enhancement 152±4150.8±22.2101.5±29.866.9±9.2163±714.02±8.19 153±4559.4±28.793.7±30.661.9±11.4233±857.72±11.15 152±4050.4±19.6101.9±29.866.9±8.7168±503.95±7.64 153±4147.9±18.6104.8±28.468.8±7.1139±382.64±5.81 151±4045.7±17.6105.6±29.069.8±6.8110±321.82±5.77 NS*<0.001*<0.001*<0.001*<0.001*<0.001* Sudden Death Events (%) 37 (2.86 ) 17 (5.25%) 6 (1.86%) 6 (1.86%) 8 (2.48%) 0.0447 *