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Antenatal Betamethasone for Women at Risk for Late Preterm Delivery
Ist Teil von
The New England journal of medicine, 2016-04, Vol.374 (14), p.1311-1320
Ort / Verlag
United States: Massachusetts Medical Society
Erscheinungsjahr
2016
Quelle
MEDLINE
Beschreibungen/Notizen
In this multicenter, randomized trial involving women at high risk for late preterm delivery, administration of betamethasone significantly reduced the rate of neonatal respiratory complications.
Antenatal glucocorticoids are widely used in obstetrics for pregnancies at risk for early preterm delivery. Their use increased especially after a consensus conference held by the National Institutes of Health in 1994, which concluded that there was strong evidence that glucocorticoids reduce adverse neonatal outcomes, including death, the respiratory distress syndrome, and other complications, when administered to women who are likely to deliver before 34 weeks of gestation.
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The recommendation was not extended to women at risk for preterm delivery after 34 weeks because of both a lack of data
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and the belief that at a threshold of . . .