Details

Autor(en) / Beteiligte

• Marklein, B
• Konthur, Z
• Häupl, T
• Cope, A
• Shlomchik, M
• Steiner, G
• Burmester, G
• Skriner, K

Titel

Toll-like receptor (TLR-7/9), MYOD88, TIR8, dependent and independent autoantigens

Ist Teil von

• Annals of the rheumatic diseases, 2010-03, Vol.69 (Suppl 2), p.A39-A39

Ort / Verlag

London: BMJ Publishing Group Ltd and European League Against Rheumatism

Erscheinungsjahr

2010

Link zum Volltext

Quelle

BMJ Journals Archiv - DFG Nationallizenzen

Beschreibungen/Notizen

• [...]autoantigens to citrullinated protein enzymes and modified enzymes are generated independently of MyoD88 Toll7, 9 and Tir8. [...]the authors found MyoD88-independent autoantigens which are not expressed in the thymus or proteins as high mobility group box proteins 1 and 2 targeted which are sensors of nucleic acidmediated innate immune responses.