Details

Autor(en) / Beteiligte

• Kim, Dong-Kyu, MD
• Eun, Kyung Mi
• Jin, Hong Ryul, MD
• Cho, Seong Ho, MD, FAAAAI
• Kim, Dae Woo, MD

Titel

Prolonged Allergen Exposure Causes TSLP-Mediated Th2-Skewing in Mouse Models of Chronic Rhinosinusitis

Ist Teil von

• Journal of allergy and clinical immunology, 2016-02, Vol.137 (2), p.AB67-AB67

Ort / Verlag

St. Louis: Elsevier Inc

Erscheinungsjahr

2016

Quelle

Electronic Journals Library

Beschreibungen/Notizen

• Results Long-term CRS models exhibited increased polypoid lesions, edematous mucosal thickness, and eosinophil infiltration compared with short-term models and showed a higher IL-4/IFN-γ ratio and IL-10 level but lower IFN-γ and IL-17A protein levels. [...]CCL24 and MMP7 gene expressions increased whereas TIMP3 expression decreased in longterm models compared to controls and short-term models.