Details

Autor(en) / Beteiligte

• Yang, Irene
• Corwin, Elizabeth J
• Brennan, Patricia A
• Jordan, Sheila
• Murphy, Jordan R
• Dunlop, Anne

Titel

The Infant Microbiome: Implications for Infant Health and Neurocognitive Development

Ist Teil von

• Nursing research (New York), 2016-01, Vol.65 (1), p.76

Ort / Verlag

United States: Lippincott Williams & Wilkins Ovid Technologies

Erscheinungsjahr

2016

Link zum Volltext

Quelle

Applied Social Sciences Index & Abstracts (ASSIA)

Beschreibungen/Notizen

• Beginning at birth, the microbes in the gut perform essential duties related to the digestion and metabolism of food, the development and activation of the immune system, and the production of neurotransmitters that affect behavior and cognitive function. The objectives of this review are to (a) provide a brief overview of the microbiome and the "microbiome-gut-brain axis"; (b) discuss factors known to affect the composition of the infant microbiome: mode of delivery, antibiotic exposure, and infant-feeding patterns; and (c) present research priorities for nursing science and clinical implications for infant health and neurocognitive development. The gut microbiome influences immunological, endocrine, and neural pathways and plays an important role in infant development. Several factors influence colonization of the infant gut microbiome. Different microbial colonization patterns are associated with vaginal versus surgical birth, exposure to antibiotics, and infant-feeding patterns. Because of extensive physiological influence, infant microbial colonization patterns have the potential to impact physical and neurocognitive development and life course disease risk. Understanding these influences will inform newborn care and parental education.