Details

Autor(en) / Beteiligte

• LaFranzo, Natalie A

Titel

Reference Standards Address Technical Challenges in DNA Resequencing

Ist Teil von

• American laboratory (Fairfield), 2015-08, Vol.47 (6), p.14

Ort / Verlag

Shelton: International Scientific Communications, Inc

Erscheinungsjahr

2015

Link zum Volltext

Quelle

EZB Electronic Journals Library

Beschreibungen/Notizen

• The extensive workflow required to analyze DNA samples using next-generation sequencing (NGS) leaves many opportunities for the introduction of variability. To achieve accurate and precise results in an NGS assay, each stage of the protocol must be routinely optimized, validated and monitored. In this regard, well-characterized reference standards are an effective route to earlier detection of diseases, noninvasive monitoring and lower sample input all of which push the technical limits of NGS. LaFranzo discusses challenges of NGS.