Details

Autor(en) / Beteiligte

• Cornel, J.H
• Ohman, E. Magnus
• Neely, Benjamin
• Clemmensen, Peter
• Sritara, Piyamitr
• Zamoryakhin, Dmitry
• Armstrong, Paul
• Prabhakaran, Dorairaj
• White, Harvey
• Fox, Keith
• Gurbel, Paul
• Roe, Matthew

Titel

IMPACT OF SMOKING STATUS ON CLINICAL OUTCOMES WITH PRASUGREL VERSUS CLOPIDOGREL IN PATIENTS WITH ACUTE CORONARY SYNDROMES MANAGED WITHOUT revascularization: INSIGHTS FROM THE TRILOGY ACS TRIAL

Ist Teil von

• Journal of the American College of Cardiology, 2013-03, Vol.61 (10), p.E159-E159

Ort / Verlag

New York: Elsevier Inc

Erscheinungsjahr

2013

Link zum Volltext

Quelle

Free E-Journal (出版社公開部分のみ）

Beschreibungen/Notizen

• Baseline characteristics Not active smoker (n=5614) Active smoker (n=1566) P Outcomes by treatment Unadjusted hazard ratio (95% CI): prasugrel vs. clopidogrel Unadjusted hazard ratio (95% CI): prasugrel vs. clopidogrel Interaction P Median age, years (IQR) 63.0 (58.0, 69.0) 59.0 (52.0, 64.0) <0.001 Female sex, % 40.3 20.4 <0.001 Diabetes mellitus, % 40.4 32.8 <0.001 Prior MI, % 42.9 47.8 <0.001 Median creatinine clearance, mL/min (IQR) 78.3 (60.4, 99.8) 90.0 (70.2, 114.0) <0.001 Angiography performed, % 39.2 53.6 <0.001 CV death/MI/stroke 1.06 (0.90-1.25) 0.54 (0.39-0.74) 0.0002 CV death 1.12 (0.88-1.43) 0.48 (0.30-0.77) 0.0018 MI 0.98 (0.80-1.21) 0.62 (0.42-0.91) 0.0403